Osseointegration properties of domestic bioactive calcium phosphate ceramics doped with silicon

Abstract Introduction The relevance of this study lies in the fact, that today search for biocompatible materials management bone defects is importance. Such could become an alternative to transplants. For replacement defects, two-phasic bioactive ceramics hydroxyapatite and β-tricalcium phosphate a very attractive biomaterial due its excellent biocompatibility osteoconductivity, but results use are quite controversial insufficient bioactivity. purpose work investigate osseointegration properties two-phase doped with silicon (HTdSi), both as single component combination platelet-rich fibrin, well comparison well-known imported analogue – BIO, which consists phosphate, also independent fibrin. In experiment, rabbits New Zealand white breed at age 3 months average weight 2.5 kg were used. terms implantation 30, 60, 90 180 days. advantages domestic bio-composite substantiated on basis clinical, radiological histological studies. Material methods Results osteointegration platelet investigated, known analog - contains Conclusions biocomposite